96-, 384- und 1536-Kanal Simultanpipettierer CyBio Well vario

CyBio Well vario - Multichannel Automated Pipetting System 96, 384 and 1536 channel simultaneous pipettor

  • High application flexibility due to enormous volume spectrum
  • Highest precision in the entire volume range
  • Unique pipetting technology prevents cross contamination

Product Details

Multiple Pipette Heads on a Solid Base

The CyBio Well vario includes an automated base which accepts different interchangeable simultaneous pipetting heads. The heads can be changed quickly and easily either at the front or the back of the instrument. The pipetting heads are automatically detected – fully preserving accuracy and precision without calibration steps.

A working volume range of four orders of magnitude allows liquid transfers from 25 nl up to 250 µl on one platform with 96, 384 or 1536 channels. The CyBio Well vario multichannel automated pipetting system adapts into any screening environment and it is compatible with all other accessories of the CyBio Well family. The innovative CyBio Composer Software supports the flexibility of the system and immediately detects new pipetting heads. 

  • Extremely flexible through enormous volume spectrum
  • Highest precision throughout the whole volume range
  • Unique pipetting technology prevents cross contamination
  • Easy application set-up using CyBio Composer software
  • Saves reagent costs with accurate low volume pipetting

Compatible Pipetting heads

Head 96/25 µl
  • Parallel pipetting of 96 samples in 96, 384 and 1536 well microplates
  • Volume freely selectable in 0.01 µl increments with a working volume up to 25 µl.
Head 96/60 µl
  • Parallel pipetting of 96 samples in 96, 384 and 1536 well microplates
  • Volume freely selectable in 0.01 µl increments with a working volume up to 60 µl.
Head 96/250 µl
  • Parallel pipetting of 96 samples in 96, 384 shallow or deep well microplates
  • Volume freely selectable in 0.01 µl increments with a working volume up to 250 µl.
Head 384/25 µl
  • Parallel pipetting of 384 samples in 384 and 1536 well microplates
  • Volume freely selectable in 0.01 µl increments with a working volume up to 25 µl.
Head 384/60 µl
  • Parallel pipetting of 384 samples in 384 and 1536 well microplates
  • Volume freely selectable in 0.01 µl increments with a working volume up to 60 µl.
Head 1536/8 µl
  • Parallel pipetting of 1536 samples in 1536 well microplates
  • Volume freely selectable in 0.01 µl increments with a working volume up to 8 µl.
Capillary Head
  • Optimized for pipetting of DMSO solutions into dry microplates
  • Available with fixed working volumes of 50, 100, 250, 500 nl with ceramic capillaries. Parallel pipetting of 96 or 384 samples in 96, 384 an 1536 well microplates due to exchangeable capillary magazines.

CyBio Well vario - 1536 Head

The 1536 pipetting head uses CyBio's unique and well-proven tip sealing system. The air displacement pistons allow the simultaneous transfer and filling of all wells in a 1536-well plate in a single step.

Specifications

 Volume range: Precision [CV in %]* of specified volume range:
Head 96/25 µl0.5-25 µl0.5 ≤ 10%
2-5 µl ≤ 2%
>5-25µl ≤ 1%
Head 96/60 µl1–60 µl3-5 µl ≤ 2%
>5-60 µl ≤ 1%
Head 96/250 µl5-250 µl25-100 µl ≤ 2%
25-250 µl ≤ 1%
Head 384/25 µl0.5-25 µl2-5 µl ≤ 2%
>5-25 µl ≤ 1
Head 384/60 µl1–60 µl3-5 µl ≤ 2%
>5-60 µl ≤ 1%
Head 1536/8 µl1–8 µl1-5 µl ≤ 3%
5-8 µl ≤ 2%
Capillary Head0.050-1 µl0.025-1,0 µl ≤ 10%

 

*The specification of precision and trueness is based on the Analytik Jena internal gravimetric and photometric standard measurement procedure, which is published as Annex B7 in the ISO IWA 15 document "Specification and method for the determination of volumetric performance of automated liquid handling systems" (www.IWA15.org). The Application Note "Photometric and Gravimetric Liquid Handling Check Procedure to determine the Random Error (Precision) and the Systematic Error (Accuracy) of Automated Liquid Handling Systems (ALHS)" describes this measuremet procedure in detail.
Every modification of this method may influence the results

Technical Data

Footprint (W x D in mm)

3-place linear transporting unit960 x 370 mm
4-place linear transporting unit1300 x 370 mm
5-place linear transporting unit1650 x 370 mm
10-place circular transporting unit700 x 895 mm

Height (mm)

772.5 mm

Pipette Channel

96, 384, 1536

Pipetting Tips

Disposable tips/capillaries

Plate Formats

96, 384, 1536

Plate Capacity

  • 3 with 3-place linear transporting unit
  • 4 with 4-place linear transporting unit
  • 5 with 5-place linear transporting unit
  • 10 with 10-place circular transporting unit

Volume Range

Wet pipetting:50 nl to 250 μl
Dry pipetting:200 nl to 250 μl

Weight

39.5 kg3, 4 and 5 place linear transporting unit
49 kg10-place circular transporting unit

Software

CyBio Composer Software

The CyBio Well vario is controlled by the CyBio Composer Software:

  • Powerful scripting environment
  • Direct access to all hardware functions and liquid handling parameters
  • Capable of connecting to databases and LIMS systems

Applications

A three, four, five or ten position carriage handles high-precision pipetting needs with high flexibility and ample deck space to run the process successfully. The high flexibility of the CyBio Composer Software supports any pipetting task.

  • Reformatting
  • Replication
  • Plate coating
  • Biochemical assays
  • ADME and cytotoxicity assays
  • Compound management Molecular Biology assays (RNA silencing)
  • Cell handling
  • uHTS MALDI Sample Preparation

Applications   
Application ReportsTechnical Reports
Precision and Accuracy of the CyBio Well vario as determined by using Artel’s Dual Dye Ratiometric Calibration Technology"How to Use" Guide for the Capillary Head of the CyBio Well vario
Start-up Routine and Tip Washing Efficiency Data of the Active Deep Well Tip Wash Station 384Presicion of Different 96-Capillary Type Magazines of the CyBio Well vario Capillary Head — Example Data
Photometric and Gravimetric Liquid Handling Check Procedure to determine the Random Error (Precision) and the Systematic Error (Accuracy) of Automated Liquid Handling Systems (ALHS)

Precision of the new Ceramic Type Capillary Magazines 384 of the CyBio Well vario Capillary Head — Example Data

 

Automated TRANSIL HSA Binding Kit on CyBio Well varioPrecision of Different 384-Capillary Type Magazines of the CyBio Well vario Capillary Head — Example Data
Optimized Washing of Disposable Tips after Transfer of DNA SamplesPrecision of The CyBio Well vario 96/25 µL Head, Example Data of Different Liquids, Pipetting Modes and Disposable Tips with Fluorescence Readout
Results of Pipetting of Small Volumes using a 384 CyBio WellPrecision of the CyBio Well vario 96/60 µl Head, Example Data of Different Liquids, Pipetting Modes and Disposable Tips with Fluorescence Readout
Performance and reliability testing of a new capillary based non-contact liquid handling system under real HTS conditionsPrecision of The CyBio Well vario 96/250 µL Head, Example Data of Different Liquids, Pipetting Modes and Disposable Tips with Fluorescence Readout
Performance and reliability testing of a new capillary based non-contact liquid handling systemPrecision of The CyBio Well vario 384/2.5 µL Head, Example Data of Different Liquids, Pipetting Modes and Disposable Tips with Fluorescence Readout
Implementation of a CyBio Integrated System to Aliquot Amplified DNA and Dispense DNA Sequencing ChemistryPrecision of the CyBio Well vario 384/25 µl Head
Precise low volume compound handling with the new Nanoliter Head of CyBio Well varioPrecision of the CyBio Well vario 384/40 µL Head, Example Data of Different Liquids, Pipetting Modes and Disposable Tips with Fluorescence Readout
 Precision of the CyBio Well vario 384/60 µL Head, Example Data of Different Liquids, Pipetting Modes and Disposable Tips with Fluorescence Readout
 Stability of the Precision of Different CyBio-Well vario Heads after Multiple Tip Washing Routines
 Measuring the Precision and Accuracy of the CyBio Well vario 384/25 μl Head using the ARTEL Multichannel Verification System (MVS)
 Performance Data demonstrating the Efficiency of the Tip Wash Station of the CyBio Well Family

Automated Pipetting System Accessories

Plate Transfer Unit

This module can be mounted to the CyBio Well or CyBio Well vario and allows the automatic relocation of a microplate to any carriage position.

Microplate Adapter

The micro plate adapter allows you to use any type of micro plates from various manufacturers on Analytik Jena devices.

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Automated Reservoir Filling

The reagent reservoirs are designed for the storage and automatically refilling of liquids, such as buffers, DMSPO, and more.

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Barcode Handling

Analytik Jena offers tailor-made solutions for the creation of barcodes, labeling of microplates, and reading of barcodes mid-process.

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Tip Wash Station

With the aid of these wash modules, tips in 96 and 384 formats can be washed automatically with pump-supported (active) inflow and drain – significantly reducing disposable costs.

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Plate Handling and Storage

Efficient microplate storage with stackers enables fully automated processing of large batches of plates and increases your walk-away time.

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Tip Changer

For high throughput applications where tip changing is necessary, the TipChanger can store up to 100 tip racks.

Downloads

Brochure CyBio Well vario (English)

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Brochure Lab Automation

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Brochure Capillary Head for CyBio Well vario (English)

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Brochure uHTS MALDI Sample Preparation (English)

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384/25 µl Head for CyBio Well vario

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1536 Pipetting Head for CyBio Well vario

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Consumables for this Device

Citations

 
 

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